Meike Kespohl Selected Research

PR-957

1/2021	Mitigated viral myocarditis in A/J mice by the immunoproteasome inhibitor ONX 0914 depends on inhibition of systemic inflammatory responses in CoxsackievirusB3 infection.
1/2020	ONX 0914 Lacks Selectivity for the Cardiac Immunoproteasome in CoxsackievirusB3 Myocarditis of NMRI Mice and Promotes Virus-Mediated Tissue Damage.
1/2020	Heart-Specific Immune Responses in an Animal Model of Autoimmune-Related Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation.
1/2018	The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.

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Meike Kespohl Research Topics

Disease

8	Myocarditis (Carditis) 01/2021 - 01/2018
7	Inflammation (Inflammations) 01/2022 - 03/2016
5	Infections 01/2022 - 01/2018
2	Neoplasms (Cancer) 01/2020 - 01/2018
2	Heart Diseases (Heart Disease) 01/2018 - 01/2018
1	Pancreatitis 01/2021
1	Fibrosis (Cirrhosis) 01/2020
1	Sepsis (Septicemia) 01/2018
1	Colitis 01/2017
1	Virus Diseases (Viral Diseases) 03/2016

Drug/Important Bio-Agent (IBA)

4	PR-957IBA 01/2021 - 01/2018
4	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021 - 03/2016
4	CytokinesIBA 01/2018 - 03/2016
2	Protein Isoforms (Isoforms)IBA 01/2021 - 03/2016
2	ChemokinesIBA 01/2020 - 01/2018
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	Cysteine (L-Cysteine)FDA Link 01/2022
1	Alanine (L-Alanine)FDA Link 01/2022
1	Analgesics (Analgesic Drugs)IBA 01/2021
1	Troponin IIBA 01/2021
1	Tramadol (K315)FDA LinkGeneric 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2020
1	Immunoglobulin G (IgG)IBA 01/2020
1	Peptides (Polypeptides)IBA 01/2020
1	Interleukin-17 (Interleukin 17)IBA 01/2020
1	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	Peptide Hydrolases (Proteases)FDA Link 01/2018
1	Macrophage Colony-Stimulating FactorIBA 01/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	Butyrates (Butyrate)IBA 01/2017

Therapy/Procedure

1	Analgesia 01/2021
1	Therapeutics 01/2020